Figure 2. Anti-apoptotic Bcl-2 family members are upregulated in Pim WT hearts.
Bcl-XL (A) and Bcl-2 (B) from mitochondrial and cytosolic fractions of NTG mouse hearts probed by immunoblot analyses to determine protein expression levels. Quantitative graphs represent relative Bcl-XL and Bcl-2 levels normalized to VDAC (mitochondrial fraction) or GAPDH (cytosolic fraction). Results are represented as mean ± SEM, n = at least 3 hearts. Student's T test: **P<0.02 for NTG vs. Pim WT Bcl-XL levels in the mitochondria fraction. *P<0.05 for NTG vs. Pim WT Bcl-2 levels in the cytosolic fraction.