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. Author manuscript; available in PMC: 2011 Apr 16.
Published in final edited form as: Circ Res. 2010 Mar 4;106(7):1265–1274. doi: 10.1161/CIRCRESAHA.109.212035

Figure 3. Mitochondrial inner membrane depolarization in cardiomyocytes induced by H2O2 is delayed by Pim-1 expression.

Figure 3

TMRE fluorescence of NRCMs under control conditions (untreated) versus oxidative stress challenge (H2O2; 100 μmol/L). NRCM (NI) = non-infected NRCM (A), GFP = NRCM infected with GFP adenovirus (B), Pim WT = NRCM infected with Pim-1 adenovirus (C), and combined plot comparing results of A, B, and C is shown in D. Quantitative graphs comparing H2O2 treated NRCM, GFP, and Pim WT at 2, 6, and 10 minutes (E). Results are represented as mean ± SEM. N = at least 3 independent experiments. One-way ANOVA: *P< 0.001 for NRCM (NI) vs. Pim WT at 2 minutes. #P<0.001 for Pim WT vs. GFP at 2 minutes. **P<0.001 for NRCM (NI) vs. GFP vs. Pim WT at 6 and 10 minutes.