Table 4.
Top 20 differentially expressed miRNAs between WT and MT
| miRNA | Sequence | WT counta | MT counta | Fold change | p-value |
|---|---|---|---|---|---|
| Higher expression in MT | |||||
| csi-miR479 | UGUGAUAUUGGUUCGGCUCAUC | 1341.6 | 1921.5 | 1.9 | 0 |
| csi-miR156a | UGACAGAAGAGAGUGAGCAC | 856.2 | 1656.1 | 2.6 | 0 |
| csi-miR167a | UGAAGCUGCCAGCAUGAUCUA | 759.6 | 1967.3 | 21.6 | 0 |
| csi-miR171b | CGAGCCGAAUCAAUAUCACUC | 28.5 | 615.4 | 4.5 | 0 |
| csi-novel-08 | UAGAUAAAGAUGAGAGAAAAA | 220.1 | 1248.5 | 1.5 | 0 |
| csi-miR166j | UCUCGGACCAGGCUUCAUUCC | 1682.9 | 2078.5 | 3.1 | 2.85E-22 |
| Lower expression in MT | |||||
| csi-miR482a | UCUUCCCUAUGCCUCCCAUUCC | 103.9 | 4.2 | 15.6 | 0 |
| csi-miR162a | UCGAUAAACCUCUGCAUCCAG | 401.0 | 25.7 | 12.4 | 0 |
| csi-miR159a | UUUGGAUUGAAGGGAGCUCUA | 307.8 | 24.8 | 3.5 | 0 |
| csi-miR390a | AAGCUCAGGAGGGAUAGCGCC | 822.2 | 235.8 | 2.5 | 0 |
| csi-miR164a | UGGAGAAGCAGGGCACGUGCA | 1894.0 | 749.0 | 1.6 | 0 |
| csi-miR167d | UGAAGCUGCCAGCAUGAUCUGA | 1362.3 | 825.8 | 1.4 | 0 |
| csi-miR172a | AGAAUCUUGAUGAUGCUGCAU | 4688.4 | 3299.7 | 1.4 | 0 |
| csi-novel-11 | UGGACAGAGAAAUCACGGUCA | 591.5 | 132.7 | 5.7 | 0 |
| csi-miR156b | CUGACAGAAGACAGUGAGCAC | 41.3 | 1.8 | 2.5 | 2.86E-27 |
| csi-miR473a | ACUCUCCCUCAAGGGCUUCGC | 168.1 | 68.1 | 1.2 | 2.01E-26 |
| csi-novel-03 | UGAAGGGCCUUUCUAGAGCAC | 90.5 | 29.6 | 8.1 | 2.87E-20 |
| csi-miR399a | UGCCAAAGGAGAAUUGCCCUG | 36.3 | 4.5 | 13.8 | 3.14E-18 |
| csi-miR482c | UCUUGCCCACCCCUCCCAUUCC | 29.0 | 2.1 | 15.6 | 8.98E-18 |
| Csi-miR164d | UGGAGAAGCAGGGCACGUGCU | 49.1 | 11.1 | 4.4 | 7.6E-17 |
a count was normalized as transcripts per million (TPM).