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. 2010 May 4;4(5):e675. doi: 10.1371/journal.pntd.0000675

Table 1. Active compounds against intracellular L.major.

L. major L. donovani Cytotoxicity CC50 THP-1
Compound code EC50 promastigote EC50 amastigote EC50 promastigote EC50 amastigote
CH872 0.1 µM 0.3 µM 0.05 µM 0.06 µM >10.0 µM
CA272 2.7 µM 0.8 µM 2.7 µM 19.0 µM >10.0 µM
NJ231 0.8 µM 11.0 µM 0.6 µM >20.0 µM >10.0 µM
CG170 1.0 µM 8.0 µM 0.1 µM 14.0 µM >10.0 µM
TE122 7.8 µM 12.0 µM 3.0 µM ≫20.0 µM >10.0 µM