Table 2. Determination of IC50 (µM) of individual human P450s for lead compounds.
| Compound | CYP3A4 | CYP2D6 |
| CH872 | >10 | >10 |
| CA272 | 3.41 | >10 |
| Ketoconazole | 0.05 | – |
| Quinidine | – | 0.02 |
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