Table 2. Plating efficiency following drug treatment.
Compound | Relative inhibitiona | % dead cells | Plating efficiency (%) |
untreated | 4.4 | 95 | |
camptothecin | 76.9 | 29.5 | 68 |
etoposide | 65.5 | 23.6 | 23 |
THQ4G | 69.6 | 20.8 | 8 |
quercetin | 69.3 | 19.8 | 53 |
PGD2 | 69.9 | 25.7 | 28 |
pentamidine | 25.5 | 10.9 | 0.4 |
pentamidine | 75.8 | 51.9 | <0.02b |
Average decrease in number of live cells as compared to untreated cultures, in multiple plating experiments.
Plating 200 live cells per well (24 wells per experiment) gave rise to no colonies. This number (0.02) assumes the next well would have given rise to a colony.