Figure 1.
Quantile–quantile plot for the test statistics for the 10 621 single-nucleotide polymorphisms (SNPs) evaluated in the Studies of Epidemiology and Risk factors in Cancer Heredity (SEARCH) dataset. The test statistic was the χ2 statistic from two-sided χ2 trend tests with 1 df. Solid circles represent the expected and observed test statistics for each SNP. Under the null hypothesis of no association at any locus, the points would be expected to follow the straight line. SNPs rs6626269 and rs4778137 are represented by a solid diamond and a solid square, respectively.