Table 1.

Characteristics of patients with available follow-up information in the Studies of Epidemiology and Risk factors in Cancer Heredity (SEARCH) study who were included in stage II of the breast cancer susceptibility genome-wide association study^*

Variable	Value
Total No. of patients	3761
Total time at risk, person-years	26 978.54
Median follow-up† (range), y	8.45 (0.47–15)
Median time at risk (range), y	7.45 (0.04–11.48)
Median time from diagnosis to study entry (range), y	1.15 (0–11.74)
No. of deaths	647
Annual mortality rate (95% CI)	0.024 (0.022 to 0.026)
5-y overall survival rate (95% CI)	0.88 (0.87 to 0.89)
Mean age at diagnosis (range), y	52 (23–69)
Age at diagnosis, No. (%)
<35 y	122 (3.24)
35–49 y	1331 (35.39)
50–64 y	2030 (53.98)
65–74 y	278 (7.39)
Histopathologic grade, No. (%)
Well differentiated	729 (19.38)
Moderately differentiated	1433 (38.10)
Poorly differentiated	871 (23.16)
Unknown	728 (19.36)
Morphological type, No. (%)
Ductal	2777 (73.84)
Lobular	564 (15.00)
Other	386 (10.26)
Unknown	34 (0.90)
Clinical stage, No. (%)
I	1850 (49.19)
II	1677 (44.59)
III or IV	156 (4.15)
Missing	78 (2.07)
ER status, No. (%)
Positive	1982 (52.70)
Negative	498 (13.24)
Missing	1281 (34.06)

^*CI = confidence interval; ER = estrogen receptor.

^†Follow-up censored at 15 years.