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. 2010 May 4;4(5):e671. doi: 10.1371/journal.pntd.0000671

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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CxFV Izabal (+) mosquitoes were inoculated intrathoracically with 3.3 log₁₀ pfu CxFV Izabal. Mock-inoculated mosquitoes were inoculated with an empty glass capillary needle, and CxFV (-) mosquitoes were not inoculated. Seven days post inoculations, all three groups were administered a WNV-infectious blood meal of 6.3 log₁₀ pfu/mL. The average WNV titer in CxFV Izabal (+) mosquitoes was significantly less than in mock-inoculated specimens at 0 DPI (Student's t-test, p = 0.016), denoted by an asterisk. At 4 DPI the average WNV titer in CxFV Izabal (+) mosquitoes was significantly higher than in CxFV (-) specimens (Student's t-test, p = 0.0048), denoted by an asterisk. Values at each time point represent the mean ± standard error of two to five mosquitoes.