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. 2008 Nov 19;28(47):12150–12162. doi: 10.1523/JNEUROSCI.2059-08.2008

Figure 2.

Figure 2.

Hsp25 molecular coding is sensitive to mutations in En1 and En2. A, D, G, J, M, The pattern of Hsp25 molecular coding in the CZ is altered in En1 and En2 mutants. Arrows in M point to ectopic stripes at the midline of lobule VII and VIII/IX of En1+/−;En2−/− mutants. B, E, H, K, N, The pattern of Hsp25 molecular coding in the NZ is altered in En1 and En2 mutants. Arrows in K and N point to ectopic stripes found only in the NZ of En2−/− and En1+/−;En2−/− mutants. The asterisk in K indicates the location of ectopic Hsp25 expression in the NZ of En2−/− mutants. C, F, I, L, O, Removal of En2 but not En1 results in ectopic expression of Hsp25 in the copula pyramidis. Asterisks in I and L indicate ectopic Hsp25 expression in the copula pyramidis, and the arrow in O points to the copula pyramidis in En1+/−;En2−/− mutants which is severely reduced in size compared with wild-type mice. P, The schematic on the left illustrates the locations of Hsp25 stripes (solid blue lines) in the CZ and NZ, and the schematic on the right illustrates the ML pattern of Hsp25 expression in the CZ and NZ. Scale bar, 1 mm (applies to all panels).