Table 1. Clinical features in seven patients with Hirayama disease.

M=male, bilat. = bilateral involvement, f-u. = follow-up, + = mild, ++ = moderate, +++ = severe

Patient	Gender	Onset age (years)	Time to bilat. (months)	Time to arrest (months)	Length of f-u. (years)	Tremor	Cold effect
1	M	15	12	36	6	+ + +	+ + +
2	M	18	24	42	9	+ + +	+ +
3	M	16	30	36	6	+ +	−
4	M	17	24	60	11	+ + +	+ + +
5	M	25	24	48	6	+ +	+ +
6	M	18	12	42	8	−	+ + +
7	M	20	24	36	6	+ + +	+ +