Table 2.
In vivo Neurochemical concentrations in hippocampus in the WT, AD and AD-treated Mice.
| Chemical | WT (n=5) | AD Reg (n=4) | AD Cel (n=3) | AD Ibu (n=8) |
|---|---|---|---|---|
| Choline | 1.09±0.20 | 1.02±0.20 | 0.88±0.10 | 1.19±0.17 |
| Glutamate | 0.27±0.07 | 0.27±0.09 | 0.26±0.08 | 0.33±0.27 |
| Glutamine | 0.08±0.03 | 0.12±0.05 | 0.07±0.03 | 0.15±0.13 |
| Myo-Inositol | 0.07±0.02 | 0.07±0.01 | 0.10±0.05 | 0.11±0.07 |
| NAA | 0.86±0.05 | 0.74±0.16* | 0.82±0.13 | 0.81±0.20 |
| Taurine | 0.38±0.09 | 0.31±0.09 | 0.19±0.11 | 0.29±0.12 |
All concentrations reported as ratios to creatine.
Reg – regulardiet; Cel – celecoxib-fed; Ibu – ibuprofen-fed
Significance (Tukey’s HSD): – Reg different than WT.