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. 2009 Dec 11;31(5):911–917. doi: 10.1093/carcin/bgp221

Fig. 3.

Fig. 3.

Effects of myricetin on UVB-induced MMP-9 activity and MMP-13 expression in SKH-1 hairless mice. (A) Myricetin inhibits UVB-induced MMP-9 activity in SKH-1 hairless mice. Proteins were extracted from isolated mouse skin samples as described in Materials and Methods. MMP-9 activity was assessed by gelatin zymography as described in Materials and Methods. (B) Myricetin inhibits UVB-induced MMP-13 expression in SKH-1 hairless mice as shown by western blotting using antibodies against MMP-13 or β-actin. Each band was densitometrically quantified by image analysis. The results are shown as means ± SEMs (n = 3). The pound (# and ##) symbols indicate a significant difference (P < 0.05 and P < 0.01, respectively) between the control and UVB-irradiated groups, whereas the asterisks (* and **) indicate a significant difference (P < 0.05 and P < 0.01, respectively) between the UVB-irradiated/myricetin-treated and UVB-only irradiated groups.