Table III.
mtDNA copy number and risk of lung cancer stratified by smoking level
| mtDNA copy number | Light smokersa |
Heavy smokersa |
|||
| Cases/controls | ORb (95% CI)b | Cases/controls | ORb (95% CI)b | P-interaction | |
| Low (≤124.79) | 68/83 | 1.0 (reference) | 43/30 | 1.6 (0.9–3.0) | |
| High (>124.79) | 75/94 | 1.1 (0.6–1.9) | 41/20 | 2.6 (1.2–5.5) | 0.37 |
a
Based on median distribution of number of cigarettes smoked per day in controls (<20 cigarettes per day versus ≥20 cigarettes per day).
b
OR and 95% CI determined by conditional logistic regression, adjusted for age at randomization and number of years smoking.