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. 2010 Mar 1;4:1–8. doi: 10.2174/1875397301004010001

Table 1.

Statistics of Prestwick Library Screening

OATP1B1
Plate number 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Mean (neg control) 5,170 5,906 5,428 7,400 6,166 4,984 4,866 6,113 5,670 6,713 6,390 6,054 6,042 9,159
STDEV (neg control) 390 1,107 807 924 579 645 451 721 634 1,150 425 605 444 921
Mean (pos control) 9,411 10,044 9,499 14,100 10,904 9,080 8,950 11,267 10,641 11,879 12,990 12,183 14,967 16,572
STDEV (pos control) 871 715 753 1,520 1,267 803 537 1,042 935 1,663 954 1,226 1,249 1,760
Sample mean 9,654 10,381 9,101 13,350 9,857 8,448 8,967 11,136 10,397 11,423 12,343 11,735 12,785 16,997
Z' factor 0.11 -0.32 -0.15 -0.09 -0.17 -0.06 0.27 -0.03 0.05 -0.63 0.37 0.10 0.43 -0.08
OATP1B3
Plate number 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Mean (neg control) 7,161 8,034 7,766 10,591 7,901 7,506 7,734 9,639 8,273 8,231 8,418 9,093 9,047 9,856
STDEV (neg control) 760 1,315 1,037 1,814 523 834 1,194 1,495 761 332 370 472 570 1,026
Mean (pos control) 26,768 31,694 27,097 31,987 28,351 25,272 30,369 26,319 26,882 30,781 31,653 34,132 34,603 32,986
STDEV (pos control) 1,704 2,889 1,778 1,212 1,789 2,271 2,257 1,792 1,171 4,063 1,281 3,003 3,917 3,014
Sample mean 26,308 26,850 23,819 33,715 26,838 25,368 25,738 29,565 26,661 29,799 29,365 33,188 31,714 36,503
Z' factor 0.62 0.47 0.56 0.58 0.66 0.48 0.54 0.41 0.69 0.42 0.79 0.58 0.47 0.48