Figure 5.

MCP-1 and TNFα concentrations decrease after tumor removal in prostate cancer patients. Plasma and releasate from platelets activated with 50 µM TRAP-6 and 100 nM PMA were isolated from whole blood collected from patients undergoing radical prostatectomy (Preoperative) and 3 months after tumor removal (3 month post-op) and analyzed by ELISA (n = 12). (A) Mean concentrations ± SEM of combined plasma and releasate concentrations are shown. (B) Mean concentrations ± SEM of plasma concentrations are shown. *P < .05 and **P < .01 versus Preoperative by Student's t test.