Table 2.

Fold Change of Tumor-Derived Proteins in Activated Platelets over Plasma in Tumor Bearing Mice.

Cytokine	Fold Change Activated Releasate: Plasma
IL-6	4.35
MCP-1	7100.49
M-CSF	12.21
MMP-2	1050.19
RANK	4467.74
RANKL	5890.61
SDF-1α	3.96
TGF-β1	1.96
TIMP-1	1155.15
TNFα	2.57
TPO	1.58

Plasma and releasates from platelets activated with 500 µM PAR-4 and 100 nM PMA were isolated from mice bearing subcutaneous LNCaP-C4-2 tumors. A human-specific microarray was used to analyze the protein concentrations that are represented as fold change of mean activated platelet releasate concentrations over mean plasma.