Table 3.

Fold Change of Host-Derived Proteins in Mice Bearing Tumors over Control Mice.

Cytokine	Plasma	Activated Platelets
G-CSF	1.71	0.94
HGF	4.53	0.46
IL-1β	3.82	1.67
IL-6	9406.73	1.21
M-CSF	1337.45	2.97
MMP-9	1.44	1.02
OPG	1.25	0.74
OPN	1.47	0.84
RANKL	1.55	1.17
SDF-1α	2208.98	1.03
TNFα	—*	0.40
TPO	—*	0.70
VEGF	1.41	0.88

Plasma and releasates from platelets activated with 500 µM PAR-4 and 100 nM PMA were isolated from mice injected with subcutaneous LNCaP-C4-2 tumors or PBS (control). A murine-specific microarray was used to analyze the protein concentrations that are represented as fold change of mean tumor concentrations over mean control.

^*None detected.