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Determination of injection site, cell quantities, and tumor incidence of experimental bone metastases of RM1 cells
| Injection site | Cell quantity | Tumor incidence |
|---|---|---|
| Femoral arterya | 3.0 × 106 | 0/4 |
| 1.5 × 106 | 0/5 | |
| 5.0 × 105 | 0/4 | |
| 2.5 × 105 | 0/7 | |
| 4.0 × 104 | 0/6 | |
| 2.0 × 104 | 0/3 | |
| Intracardiaca | 3.0 × 105 | 0/4 |
| 1.5 × 105 | 0/3 | |
| Intratibial | 2.5 × 105 | 5/5 |
| 1.0 × 104 | 4/4 | |
| 1.0 × 103 | 10/10 |
Soft tissue tumors formed at site of injection due to cell spillage
