Table 1.
After pVAX-hSlo and pSMAA-hSlo treatment in rats 20 most up-regulated genes, respectively
| Gene Expression Change |
|||
|---|---|---|---|
| Gene Symbol | Gene | Log-Fold | Fold |
| pVAX-hSlo: | |||
| LOC362442* | Not available | 6.68 | 44.59 |
| Muc10* | Mucin 10, submandibular gland salivary mucin | 6.40 | 40.99 |
| RGD:708577* | Common salivary protein 1 | 6.06 | 36.70 |
| Vcsa1* | Variable coding sequence A1 | 5.56 | 30.86 |
| Not available* | Not available | 3.55 | 12.61 |
| Oit1_predicted* | Oncoprotein induced transcript 1 (predicted) | 2.99 | 8.92 |
| Igha* | Ig heavy chain (α polypeptide) | 2.84 | 8.06 |
| Cldn10_predicted* | Claudin 10 (predicted) | 2.77 | 7.69 |
| Tacstd1* | Tumor-associated calcium signal transducer 1 | 2.75 | 7.57 |
| Alas2† | Aminolevulinic acid synthase 2 | 2.70 | 7.29 |
| S100a9† | S100 calcium binding protein A9 (calgranulin B) | 2.50 | 6.25 |
| RGD1310209_predicted† | Similar to KIAA1324 protein (predicted) | 2.35 | 5.54 |
| LOC498228† | Not available | 2.27 | 5.16 |
| Hemgn | Hemogen | 2.21 | 4.87 |
| Krt1-18† | Keratin complex 1, acidic, gene 18 | 2.18 | 4.75 |
| Not available† | Not available | 2.17 | 4.73 |
| Not available | Not available | 2.10 | 4.39 |
| Hbb† | Hemoglobin β chain complex | 2.08 | 4.33 |
| Myo5c_predicted | Myosin VC (predicted) | 2.05 | 4.20 |
| RGD:1359209 | Globin, α | 2.03 | 4.12 |
| Acdc | Adipocyte complement related protein of 30 kDa | 2.03 | 4.11 |
| pSMAA-hSlo: | |||
| Muc10* | Mucin 10, submandibular gland salivary mucin | 7.07 | 50.05 |
| RGD:708577* | Common salivary protein 1 | 6.70 | 44.90 |
| LOC362442* | Not available | 6.34 | 40.16 |
| Vcsa1* | Variable coding sequence A1 | 6.06 | 36.70 |
| Pip† | Prolactin induced protein | 4.04 | 16.28 |
| Stfa3_predicted | Stefin A3 (predicted) | 3.96 | 15.66 |
| Not available* | Not available | 3.81 | 14.51 |
| Krtdap | Keratinocyte differentiation associated protein | 3.69 | 13.59 |
| Vcsa2 | Variable coding sequence A2 | 3.60 | 12.98 |
| Not available† | Not available | 3.44 | 11.83 |
| Oit1_predicted* | Oncoprotein induced transcript 1 (predicted) | 3.20 | 10.22 |
| Tacstd1* | Tumor-associated calcium signal transducer 1 | 3.19 | 10.18 |
| RGD:1359664 | Type II keratin Kb1 | 3.18 | 10.13 |
| Not available | Not available | 3.16 | 10.01 |
| Not available | Not available | 3.11 | 9.65 |
| Expi† | Extracellular peptidase inhibitor | 3.03 | 9.18 |
| Not available | Not available | 3.00 | 9.03 |
| Igha* | Ig heavy chain (a polypeptide) | 2.93 | 8.61 |
| Cldn10_predicted* | Claudin 10 (predicted) | 2.82 | 7.97 |
| Not available | Not available | 2.80 | 7.86 |
| RGD:1303044† | Type I keratin KA15 | 2.79 | 7.77 |
*
Top 20 changed genes per treatment group.
†
Genes changed in 2 treatment groups.