Table 2.
After pVAX-hSlo and pSMAA-hSlo treatment in rats 20 most down-regulated genes, respectively
| Gene Expression Change |
|||
|---|---|---|---|
| Gene Symbol | Gene | Log-Fold | Fold |
| pVAX-hSlo: | |||
| RGD:1303126* | SPARC-related modular calcium binding protein 1 | −2.40 | 5.77 |
| Col6a3_predicted | Procollagen, type VI, α3 (predicted) | −2.07 | 4.28 |
| Ptrf_predicted* | Polymerase I and transcript release factor (predicted) | −2.06 | 4.23 |
| Nedd4a† | Neural precursor cell gene 4A | −1.99 | 3.98 |
| Lcn2 | Lipocalin 2 | −1.97 | 3.89 |
| App† | Amyloid β (A4) precursor protein | −1.82 | 3.30 |
| Cav† | Caveolin | −1.74 | 3.04 |
| Prnd_predicted* | Prion protein dublet (predicted) | −1.72 | 2.95 |
| Not available* | Not available | −1.72 | 2.94 |
| Mfap2_predicted† | Microfibrillar-associated protein 2 (predicted) | −1.71 | 2.91 |
| RGD:1359529 | Similar to hypothetical protein dJ465N24.2.1 | −1.68 | 2.83 |
| Mmp3* | Matrix metallopeptidase 3 | −1.66 | 2.75 |
| Not available | Not available | −1.64 | 2.70 |
| LOC294435 | Not available | −1.59 | 2.54 |
| Aebp1_predicted | AE binding protein 1 (predicted) | −1.59 | 2.53 |
| Nisch_predicted | Nischarin (predicted) | −1.57 | 2.46 |
| Mtmr1_predicted† | Myotubularin related protein 1 (predicted) | −1.51 | 2.27 |
| Col18a1 | Collagen, type XVIII, α 1 | −1.48 | 2.20 |
| Eef1a1 | Eukaryotic translation elongation factor 1 α 1 | −1.46 | 2.14 |
| Not available | Not available | −1.46 | 2.13 |
| RGD1309414_predicted | Similar to KIAA0913 protein (predicted) | −1.46 | 2.13 |
| pSMAA-hSlo: | |||
| RGD:1303126* | SPARC-related modular calcium binding protein 1 | −2.00 | 4.00 |
| Ptrf_predicted* | Polymerase I and transcript release factor | −1.96 | 3.86 |
| LOC499533 | Not available | −1.77 | 3.15 |
| Prnd_predicted* | Prion protein dublet (predicted) | −1.66 | 2.77 |
| Mfap2_predicted | Microfibrillar-associated protein 2 (predicted) | −1.66 | 2.75 |
| RT1-Bb | RT1 class II locus Bb | −1.65 | 2.73 |
| Not available* | Not available | −1.61 | 2.60 |
| Mmp3* | Matrix metallopeptidase 3 | −1.53 | 2.35 |
| Not available | Not available | −1.52 | 2.31 |
| LOC360840† | Not available | −1.48 | 2.20 |
| Scgb2a1 | Secretoglobin, family 2A, member 1 | −1.45 | 2.11 |
| Not available | Not available | −1.44 | 2.08 |
| LOC503252 | Not available | −1.44 | 2.08 |
| Not available | Not available | −1.44 | 2.07 |
| LOC498539 | Not available | −1.43 | 2.05 |
| Ap1s1_predicted | Adaptor protein complex AP-1, Σ 1 | −1.43 | 2.05 |
| Lamc1† | Laminin, γ 1 | −1.43 | 2.05 |
| LOC360596 | Not available | −1.42 | 2.03 |
| Gnb2† | Guanine nucleotide binding protein, β polypeptide 2 | −1.42 | 2.00 |
| Fgfr1 | Fibroblast growth factor receptor 1 | −1.40 | 1.97 |
| Tm9sf4_predicted | Transmembrane 9 superfamily protein member 4 | −1.40 | 1.97 |
*
Top 20 changed genes per treatment group.
†
Genes changed in 2 treatment groups.