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Aortic arch patterning defects in E14.5-E18.5 embryos
| Genotype | n | Abnormal (%) |
HAA | Ab-RSA | IAA-B and RAA |
|---|---|---|---|---|---|
| Wild-type | 43 | 0 | 0 | 0 | 0 |
| Raldh2+/− | 35 | 1 (3) | 1 | 0 | 0 |
| Tbx1+/− | 36 | 9 (25) | 4 | 4 | 1 |
| Raldh2+/−;Tbx1+/− | 36 | 7 (19) | 2 | 4 | 1 |
Ab-RSA, aberrant origin of the right subclavian artery including retroesophageal right subclavian artery; HAA, high aortic arch; IAA-B, interrupted aortic arch type B; RAA, right aortic arch.
