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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Am J Surg. 2010 Apr;199(4):542–548. doi: 10.1016/j.amjsurg.2009.11.002

Figure 3.

Figure 3

CsA protects mitochondrial membrane integrity in rat lung microvascular endothelial cells (RLMEC). Fluorescence microscopy images of the mitochondrial membrane potential indicator JC-1 in its monomeric (green) and dimeric (red) forms are shown. BAK (BH3) transfection leads to the collapse of mitochondrial membrane potential showing predominantly monomeric forms. CsA (10nM) treatment prevents the collapse of mitochondrial membrane potential evidenced by the restoration of dimeric form-red fluorescence.