Table 1.

Demographic and clinical characteristics of brain-dead organ donors

Characteristic	Preload Unresponsive Donors (PPV ≤13%) (n = 11)	Preload Responsive Donors (PPV >13%) (n = 10)	All Donors (n = 21)	p Value
Age, yrs, mean (sd)	48.5 (20)	58.2 (13.5)	53 (18)	NS
Male gender, n (%)	5 (45.5)	7 (70)	12 (58)	NS
Race, n (%)
Caucasian	9 (82)	7 (70)	16 (76)	NS
African American	2 (18)	3 (30)	5 (24)
Mechanism of brain death, n (%)
Intracerebral hemorrhage	4 (36.4)	4 (40)	8 (38.2)	NS
Stroke	—	1 (10)	1 (5)
Subarachnoid hemorrhage	2 (18.2)	3 (30)	5 (24.1)
Head injury	1 (9.1)	1 (10)	2 (9.6)
Gunshot injury	2 (18.2)	1 (10)	3 (14.1)
Other	2 (18.2)	—	2 (9.1)
Acute Physiology and Chronic Health Evaluation II score, mean (sd)	22.4 (5.4)	19.2 (9.4)	21 (7.4)	NS
Comorbidities, n (%)
Hypertension	3 (27.3)	7 (70)	10 (48.6)	.05
Diabetes mellitus	3 (27.27)	2 (20)	5 (23.6)	NS
Peripheral vascular disease	1 (9.1)	1 (10)	2 (9.6)	NS
Smoking history	7 (64)	4 (40)	11 (52)	NS
Coronary artery disease	2 (18.2)	—	2 (9.1)	NS
Chronic kidney disease	1 (9.1)	—	1 (4.5)	NS
Cancer history	3 (27.3)	1 (10)	4 (18.3)	NS
Medication use, n (%)
Corticosteroid	9 (82)	5 (50)	14 (66)	NS
Thyroxine	11 (100)	9 (90)	20 (95)	NS
Fluid balance, L, mean (sd)
Total input	6.3 (3.4)	5.0 (3.3)	5.8 (3.3)	NS
Urine output	3.5 (2.1)	3.9 (2.9)	3.7 (2.40)	NS
Net balance	2.7 (2.31)	1.4 (1.6)	2.1 (2.1)	NS
Time from brain death to first cytokine assay, hrs, mean (sd)	8.4 (8.6)	5.1 (2.9)	6.8 (6.4)	NS
Time from brain death to organ procurement, hrs, mean (sd)	20.3 (8.0)	19.3 (9.5)	20 (8.4)	NS
Organs
Procured, n (mean)	52 (4.7)	32 (3.2)	84 (4.0)	NS
Transplanted, n (mean)	41 (3.7)	18 (1.8)	59 (2.8)	.034

PPV, pulse pressure variation; NS, not significant.