Table 2.
Donor hemodynamics by preload response characteristics
| Hemodynamic Variablea | Preload Unresponsive Donors (PPV ≤13%) (n = 11) | Preload Responsive Donors (PPV >13%) (n = 10) | All Donors (n = 21) | p Value |
|---|---|---|---|---|
| Heart rate, beats/min | 91 (17) | 107 (17) | 95.3 (17.3) | NS |
| Systolic blood pressure, mm Hg | 134 (25.5) | 131.4 (19.4) | 133 (22.4) | NS |
| Diastolic blood pressure, mm Hg | 64.3 (18) | 66 (10.5) | 65 (15) | NS |
| Mean arterial pressure, mm Hg | 88 (19.5) | 84 (13) | 86 (16) | NS |
| Cardiac index, L/min/m2 | 4.3 (3) | 3.3 (1.2) | 3.8 (2.2) | NS |
| Stroke volume index, mL/m2/beat | 49 (36.2) | 31.4 (9.6) | 41 (28.4) | NS |
| Systemic vascular resistance index, dyne·sec/cm5/m2 | 2008.5 (1071) | 2267 (917.66) | 2125 (987) | NS |
| Oxygen delivery index, mL/min/m2 | 585.2 (365) | 468.6 (214) | 526.9 (290) | NS |
| PPV, % | 8.1 (3.4) | 19.2 (5.0) | 13.5 (7.0) | — |
| Superior vena caval oxygen saturation, % | 87.4 (8.6) | 86 (6.3) | 87 (7.6) | NS |
| Lactate, mmol/L | 2.6 (0.8) | 2.7 (2.5) | 2.7 (1.8) | NS |
| Vasopressor, norepinephrine unitsb | 0.1 (0.3) | 0.4 (0.4) | 0.2 (0.4) | .04 |
PPV, pulse pressure variation; NS, not significant.
a
All hemodynamic variables are reported as mean (sd);
b
vasopressor doses among various donors were standardized using the following criteria: We assumed 5 μg/kg/min of dopamine = 1 μg/kg of phenylephrine = 0.2 norepinephrine units, and 0.04 μg/min of vasopressin = 0.3 norepinephrine units.