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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Nat Immunol. 2010 Jan 19;11(2):114–120. doi: 10.1038/ni.1837

Figure 3.

Figure 3

Roles of Bcl-6 and Blimp-1 in T cell differentiation. (a,b) Two proposed models of effector CD4+ T cell differentiation: model 1 (a) and model 2 (b). in b, the partial TH1, TH2, Treg and TH17 characteristics of TFH cells are not shown, for simplicity. (c) A model of CD8+ T cell effector and memory differentiation highlighting the similarities to CD4+ T cells. Dotted lines and question marks indicate uncertainty. +Ag, antigen stimulation; SLeC, short-lived effector cell; MPeC, memory precursor effector cell.