Figure 6.

Periodic path modules. (a) The fraction of periodic targets among all perturbed genes (red) of a given transcription factor, and the fraction found in enriched motifs (blue) in overexpression data, showing all transcription factors with at least one periodically expressed target. Two path modules overrepresented in periodic genes for the PPI-TRI-TRI path in overexpression data (b) and the PPI-PhI-TRI path in deletion data (c). TRI are in red, PPI in blue and PhI in green. The dotted gray lines represent coexpression links while yellow lines represent deletion or overexpression links.