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. Author manuscript; available in PMC: 2011 Mar 9.
Published in final edited form as: Biochemistry. 2010 Mar 9;49(9):2018–2030. doi: 10.1021/bi902027z

Figure 6.

Figure 6

Model description of XWKK-polyU logKobs and SKobs as a function of pH. (A) LogKobs for XWKK binding to polyU at 25 °C and 24.4 mM Na+ are plotted as a function of pH. KWKK logKobs was directly determined from reverse titration data (●), whereas HWKK logKobs (○) was interpolated via eq. 6 using the parameters in Table 1. Curves represent the global nonlinear least squares fit of the combined logKobs vs [salt] and pH data in Figure 6 to eq. 9 (Table 2). (B) SKobs, as reported in Table 1, is plotted as a function of pH for KWKK and HWKK. Curves represent the fits to eq. 13 - 14 using the parameters in Table 2.