Skip to main content
. Author manuscript; available in PMC: 2011 Mar 9.
Published in final edited form as: Biochemistry. 2010 Mar 9;49(9):2018–2030. doi: 10.1021/bi902027z

Table 2.

Global fit parameters describing the pH dependence of logKobs and SKobs versus amino acid compositiona

peptide logK0
(1 M Na+)		 pKa
ψ Histidine αNH3+
KWKK 0.77 ± 0.01 0.02 ± 0.07 --- 7.57 ± 0.08
HWKK 0.76 ± 0.03 0.12 ± 0.10 5.75 ± 0.18 7.86 ± 0.13
a

Values reported are the globally fitted values to eq. 13 for all reverse titration and salt back data in Figure 5 (N ≈ 70 – 71 data points each). Errors represent 95% confidence intervals for the global fit.