Table 1.
Human Selenoproteins
| Selenoproteins | Accession number | Subcellular location |
|---|---|---|
| Deiodinase 1 (D1) | NP_000783.2 | Plasma membrane |
| Deiodinase 2 (D2) | NP_054644.1 | ER membrane |
| Deiodinase 3 (D3) | NP_001353.3 | Plasma membrane |
| Glutathione peroxidase 1 (GPx1) | CAA68491.1 | Cytosol, mitochondria |
| Glutathione peroxidase 2 (GPx2) | NP_002074.2 | Cytosol |
| Glutathione peroxidase 3 (GPx3) | NP_002075.2 | Secreted |
| Glutathione peroxidase 4 (GPx4) | NP_002076.2 | Cytosol, mitochondria, nucleus |
| Glutathione peroxidase 6 (GPx6) | NP_874360.1 | Unknown |
| Methionine sulfoxide reductase (MsrB1, SelR, SelX) | NP_057416.1 | Cytosol, nucleus |
| Selenoprotein H (SelH) | NP_734467.1 | Nucleus |
| Selenoprotein I (SelI) | NP_277040.1 | Unknown |
| Selenoprotein K (SelK) | NP_067060.2 | ER and plasma membrane |
| Selenoprotein M (SelM) | NP_536355.1 | ER lumen |
| Selenoprotein N (SelN) | NP_996809.1 | ER membrane |
| Selenoprotein O (SelO) | NP_113642.1 | Unknown |
| Selenoprotein P (SelP) | NP_001087195.1 | Secreted |
| Selenoprotein S (SelS) | NP_060915.2 | ER and plasma membrane |
| Selenoprotein T (SelT) | NP_057359.2 | ER membrane |
| Selenoprotein V (SelV) | NP_874363.1 | Unknown |
| Selenoprotein W (SelW) | NP_003000.1 | Cytosol |
| 15-kDa selenoprotein (Sep15) | NP_004252.2 | ER lumen |
| Selenophosphate synthase 2 (SPS2) | NP_036380.2 | Cytosol |
| Thioredoxin reductase 1 (TR1, TrxR1, TxnRd1) | NP_001087240.1 | Cytosol, nucleus |
| Thioredoxin glutathione reductase (TGR, TR2, TrxnRd3) | XP_001130163.1 | Cytosol |
| Thioredoxin reductase 3 (TR3, TxnRd2) | NP_006431.2 | Mitochondria |