Table 2. Structures related to Mtb H37Rv identified in the PDB.
| PDB code | Source | Resolution (Å) | No. of subunits in ASU | Ligand† | Sequence identity to Mtb (%) | Reference |
|---|---|---|---|---|---|---|
| 1g98 | Oryctolagus cuniculus | 1.9 | 2 | PA5 | 46 | Jeffery et al. (2001 ▶) |
| 1gzd | Sus scrofa | 2.5 | 1 | SO42− | 49 | Davies & Muirhead (2002 ▶) |
| 1gzv | S. scrofa | 3.5 | 1 | PA5 | 46 | Davies & Muirhead (2002 ▶) |
| 1hm5 | O. cuniculus | 1.8 | 2 | No ligand | 45 | Arsenieva & Jeffery (2002 ▶) |
| 1iat | Homo sapiens | 1.6 | 1 | BME, SO42− | 46 | Read et al. (2001 ▶) |
| 1jlh | H. sapiens | 2.1 | 4 | 48 | Cordeiro et al. (2003 ▶) | |
| 1koj | O. cuniculus | 1.9 | 2 | 5-Phospho-D-arabinohydroxamic acid | 45 | Arsenieva et al. (2002 ▶) |
| 1n8t | O. cuniculus | 2.5 | 2 | 48 | Davies & Muirhead (2003 ▶) | |
| 1q50 | Leishmania mexicana | 2.6 | 1 | 48 | Cordeiro et al. (2004 ▶) | |
| 1qxj | Pyrococcus furiosus | 1.8 | 2 | Ni2+ | 3 | Swan et al. (2003 ▶) |
| 1qxr | P. furiosus | 1.7 | 2 | PA5, Ni2+ | 3 | Swan et al. (2003 ▶) |
| 1qy4 | P. furiosus | 1.8 | 2 | Ni2+, 6-phosphogluconic acid | 3 | Swan et al. (2003 ▶) |
| 1t10 | L. mexicana mexicana | 2.3 | 1 | F6P | 48 | Cordeiro et al. (2004 ▶) |
| 1tzb | Pyrobaculum aerophilum strain IM2 | 1.2 | 2 | GOL, SO42− | 2 | Swan et al. (2004 ▶) |
| 1tzc | P. aerophilum strain IM2 | 1.5 | 2 | GOL, PA5, SO42− | 6 | Swan et al. (2004 ▶) |
| 1u0e | Mus musculus | 1.6 | 2 | GOL, BME, SO42− | 47 | Solomons et al. (2004 ▶) |
| 1u0f | M. musculus | 1.6 | 2 | α-D-G6Q, G6Q, SO42−, BME, GOL | 47 | Solomons et al. (2004 ▶) |
| 1u0g | M. musculus | 1.7 | 2 | SO42−, erythose-4-phosphate, BME, GOL | 47 | Solomons et al. (2004 ▶) |
| 1x7n | Pyrococcus furiosus | 1.9 | 1 | PA5, Mn2+ | 3 | Berrisford et al. (2004 ▶) |
| 1x82 | P. furiosus | 1.5 | 1 | PA5 | 3 | Berrisford et al. (2004 ▶) |
| 1x8e | P. furiosus | 2.8 | 2 | 3 | Berrisford et al. (2004 ▶) | |
| 1x9h | Pyrobaculum aerophilum | 1.5 | 2 | GOL, F6P, SO42− | 6 | Swan et al. (2004 ▶) |
| 1x9i | P. aerophilum | 1.2 | 2 | GOL, G6Q | 6 | Swan et al. (2004 ▶) |
| 1xtb | O. cuniculus | 2.0 | 2 | D-Sorbitol-6-phosphate | 49 | Lee & Jeffery (2005 ▶) |
| 2cer | Sulfolobus solfataricus | 2.3 | 2 | ACT, (5R,6R,7S,8S)-5-(hydroxymethyl)-2-(2-phenylethyl)-1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-6,7,8-triol | 5 | Gloster et al. (2006 ▶) |
| 2cet | Thermotoga maritima | 2.0 | 2 | Ca2+, (5R,6R,7S,8S)-5-(hydroxymethyl)-2-(2-phenylethyl)-1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-6,7,8-triol, ACT | 1 | Gloster et al. (2006 ▶) |
| 2cvp | M. musculus | 1.8 | 1 | GOL, ACT | 47 | Tanaka et al. (2006 ▶) |
| 2cxn | M. musculus | 1.4 | 1 | GOL, phosphate ion | 47 | Tanaka et al. (2006 ▶) |
| 2cxo | M. musculus | 1.8 | 1 | GOL, D-4-phosphoerythronic acid | 47 | Tanaka et al. (2006 ▶) |
| 2cxp | M. musculus | 1.7 | 1 | GOL, arabinose-5-phosphate | 47 | Tanaka et al. (2006 ▶) |
| 2cxq | M. musculus | 1.5 | 1 | GOL, D-sorbitol-6-phosphate | 47 | Tanaka et al. (2006 ▶) |
| 2cxr | M. musculus | 1.7 | 1 | GOL, 6-phosphogluconic acid | 47 | Tanaka et al. (2006 ▶) |
| 2cxs | M. musculus | 1.5 | 1 | GOL, F6P | 47 | Tanaka et al. (2006 ▶) |
| 2cxt | M. musculus | 1.5 | 1 | GOL, F6P | 47 | Tanaka et al. (2006 ▶) |
| 2cxu | M. musculus | 1.6 | 1 | GOL, phosphate ion | 47 | Tanaka et al. (2006 ▶) |
| 2gc0 | Pyrococcus furiosus | 2.0 | 2 | 5-Phospho-D-arabinohydroxamic acid, Zn2+ | 3 | Berrisford et al. (2006 ▶) |
| 2gc1 | P. furiosus | 2.0 | 2 | Zn+2, D-sorbitol-6-phosphate | 3 | Berrisford et al. (2006 ▶) |
| 2gc2 | P. furiosus | 2.1 | 2 | D-F6P (open form), Zn2+ | 3 | Berrisford et al. (2006 ▶) |
| 2gc3 | P. furiosus | 2.1 | 2 | α-D-Mannose-6-phosphate, Zn2+ | 3 | Berrisford et al. (2006 ▶) |
| 2o2c | Trypanosoma brucei brucei | 1.6 | 1 | GOL, G6Q | 16 | Arsenieva et al. (2002 ▶) |
| 2o2d | T. brucei brucei | 1.9 | 1 | GOL, citric acid | 19 | Arsenieva et al. (2002 ▶) |
| 2q8n | Thermotoga maritima MSB8 | 1.8 | 1 | Nonaethylene glycol, Cl−, SO42− | 21 | Joint Center for Structural Genomics (unpublished) |
| 3cv0 | Trypanosoma brucei | 2.0 | 1 | 1,2-Ethanediol | 7 | Sampathkumar et al. (2008 ▶) |
| 3cvl | T. brucei | 2.2 | 1 | 7 | Sampathkumar et al. (2008 ▶) | |
| 3ff1 | Staphylococcus aureus subsp. aureus COL | 1.6 | 1 | Na+, G6Q | 16 | S. M. Anderson, J. S. Brunzelle, O. Onopriyenko, S. Peterson, W. F. Anderson & A. Savchenko (unpublished) |
| 3hjb | Vibrio cholerae | 1.5 | 1 | Ca2+, Cl−, tetraethylene glycol, Na+, di(hydroxyethyl)ether | 51 | Center for Structural Genomics of Infectious Diseases (unpublished) |
| 3ifs | Bacillus anthracis | 2.0 | 1 | SO42−, Cl−, triethylene glycol, Li+ | 19 | Center for Structural Genomics of Infectious Diseases (unpublished) |
| 2wu8 | Mycobacterium tuberculosis H37Rv | 1 | SO42− | This work |
†
PA5, 5-phosphoarabinonic acid; F6P, fructose-6-phosphate; GOL, glycerol; BME, β-mercaptoethanol; G6Q, glucose-6-phosphate; ACT, acetate ion.