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. 1998 Aug 22;317(7157):516–519. doi: 10.1136/bmj.317.7157.516

Table 4.

Predictive values of optimal threshold concentrations* of brain natriuretic peptide and N-terminal atrial natriuretic peptide for identifying left ventricular systolic dysfunction

Patient group  Brain natriuretic peptide
N-terminal atrial natriuretic peptide
Optimal threshold (pg/ml} Positive predictive value (95% CI) Negative predictive value (95% CI) Optimal threshold (ng/ml) Positive predictive value (95% CI) Negative predictive value (95% CI)
Moderate or severe left ventricular dysfunction 46 0.69 (0.44 to 0.94) 0.55 (0.42 to 0.68) 4.4 0.52 (0.32 to 0.72) 0.51 (0.36 to 0.66)
Severe left ventricular dysfunction 32 0.35 (0.12 to 0.58) 0.92 (0.81 to 1.03) 1.4 0.22 (0.8 to 0.36)  1.00
Fractional shortening <25% 46 0.56 (0.24 to 0.88) 0.86 (0.74 to 0.98) 5.4 0.31 (0.08 to 0.54) 0.82 (0.68 to 0.96)
*

Optimal indicates the peptide concentration giving the best combination of sensitivity and specificity.