Figure 7. An mRpL34 transgene rescues external eye defects associated with Df(2R)Dg²⁴⁸.

SEM of two day old female adult eyes (A–E) and the corresponding histology (A′–E′). A wild type eye shows the ordered array of ommatidia both on the surface (A) and within the retina (A′). On the surface, a Dg⁰⁴³ eye (B) has a small region (arrow) of mispatterning of ommatidia. Within the Dg⁰⁴³ retina (B′) the patterning of the retina is normal. The surface of a Dg⁰⁸⁶ eye (C) as well as the within the retina (C′) shows a normal pattern of ommatidia. The Dg⁰⁸⁶ eye shape is more spherical relative to wild type. A Df(2R)Dg²⁴⁸ mosaic eye has a grossly disrupted array of ommatidia on its surface (D) as well as within (D′). Expression of an mRpL34 transgene in a Df(2R)Dg²⁴⁸ mosaic eye significantly rescues the external and internal eye disruption (E and E′). The scale bars are 100 µm (A–E); 10 µm (A′–E′). Line marks the retinal equator in A′ and C′.