Table 2.
Percentage of HLA-DR positive epithelial and CD80 positive cells (antigen-presenting cells) and mean fluorescence intensity (MFI) of ocular surface inflammatory molecules obtained by impression cytology at month 1 and 3 of follow-up in eyes with successful and failed surgery.
| % of HLA-DR positive cells and their MFI median values (minimum-maximum) | 3 months after surgery | 6 months and 12 months after surgery | ||||
|---|---|---|---|---|---|---|
| Success (n = 23) | Failure (n = 7) | P | Success (n = 21) | Failure (n = 9) | P | |
| % of HLA-DR positive epithelial cells at month 1 | 52 (11–97) | 83 (65–83) | .058 | 58 (11–97) | 52 (32–83) | .960 |
|
| ||||||
| MFI of HLA-DR on epithelial cells at month 1 | 14834 (2742–55237) | 16444 (3019–34050) | .906 | 21369 (2742–55237) | 8094 (3019–16444) | .036 |
|
| ||||||
| % of HLA-DR positive CD80 cells at 1 month | 64.5 (26–97) | 82 (70–96) | .128 | 65 (26–97) | 68 (44–85) | .926 |
|
| ||||||
| MFI of HLA-DR on CD80 positive cells at 1 month | 2686 (592–23661) | 2082 (1861–22194) | .844 | 2728 (592–23661) | 2114 (1459–11540) | .514 |
|
| ||||||
| % of HLA-DR positive epithelial cells at month 3 | 56 (7–93) | 56 (30–84) | .762 | 55 (7–88) | 69 (30–93) | .402 |
|
| ||||||
| MFI of HLA-DR on epithelial cells at month 3 | 5178 (533–20735) | 3450 (835–8747) | .493 | 6150 (533-20735) | 2885 (1835–18634) | .082 |
|
| ||||||
| % of HLA-DR positive CD80 cells at 3 month | 67 (48–99) | 67 (43–82) | .401 | 66 (48-83) | 73 (43–99) | .920 |
|
| ||||||
| MFI of HLA-DR on CD80 positive cells at 3 month | 4456 (1028–17943) | 6106 (1445–17808) | .595 | 6050 (1028–17943) | 2755 (1340–17808) | .188 |
Mann-Whitney U test; significant at P < .05.