Table 2.
Forty-six genes from the reduced QTL interval on chromosome 3 contain one or more potentially functional SNPs
| Gene symbol | Gene start (Mbp) | Gene end (Mbp) | 3′UTR SNP | Coding non-synonymous SNPs | Locus region SNP |
|---|---|---|---|---|---|
| Adora3 | 105.67 | 105.73 | Yes | ||
| I830077J02Rik | 105.73 | 105.74 | Yes | Yes | |
| Atp5f1 | 105.75 | 105.76 | Yes | ||
| Wdr77 | 105.76 | 105.77 | Yes | ||
| Ovgp1 | 105.78 | 105.79 | Yes | ||
| Dennd2d | 106.29 | 106.30 | Yes | ||
| Kcna10 | 106.99 | 107.00 | Yes | Yes | |
| Gm131 | 107.01 | 107.02 | Yes | ||
| Ntng1 | 109.58 | 109.95 | Yes | ||
| LOC625585 | 111.68 | 111.88 | Yes | ||
| EG229746 | 112.11 | 112.11 | Yes | Yes | |
| EG433643 | 112.86 | 112.86 | Yes | ||
| Col11a1 | 113.73 | 113.92 | Yes | Yes | |
| Olfm3 | 114.61 | 114.83 | Yes | ||
| Edg1 | 115.41 | 115.42 | Yes | ||
| Dph5 | 115.59 | 115.63 | Yes | ||
| Slc30a7 | 115.65 | 115.71 | Yes | ||
| Vcam1 | 115.81 | 115.83 | Yes | Yes | Yes |
| Dbt | 116.22 | 116.25 | Yes | ||
| Lrrc39 | 116.27 | 116.29 | Yes | Yes | Yes |
| Ccdc76 | 116.28 | 116.32 | Yes | Yes | |
| Sass6 | 116.3 | 116.33 | Yes | ||
| Slc35a3 | 116.37 | 116.42 | Yes | ||
| Frrs1 | 116.56 | 116.61 | Yes | Yes | |
| Palmd | 116.56 | 116.61 | Yes | ||
| 1700061I17Rik | 116.77 | 116.78 | Yes | Yes | |
| D3Bwg0562e | 117.02 | 117.06 | Yes | Yes | |
| Alg14 | 120.99 | 121.06 | Yes | ||
| Cnn3 | 121.13 | 121.16 | Yes | ||
| Slc44a3 | 121.16 | 121.24 | Yes | ||
| LOC100043726 | 122.08 | 122.09 | Yes | ||
| Synpo2 | 122.78 | 122.94 | Yes | ||
| Sec24d | 122.97 | 123.07 | Yes | Yes | Yes |
| G430022H21Rik | 123.07 | 123.09 | Yes | Yes | |
| Prss12 | 123.15 | 123.21 | Yes | ||
| EG668804 | 123.21 | 123.21 | Yes | ||
| Ndst3 | 123.23 | 123.38 | Yes | Yes | Yes |
| EG668809 | 123.99 | 124.00 | Yes | ||
| 1700006A11Rik | 124.1 | 124.13 | Yes | Yes | Yes |
| Ndst4 | 125.14 | 125.43 | Yes | ||
| Ugt8a | 125.57 | 125.64 | Yes | Yes | |
| Arsj | 126.07 | 126.14 | Yes | ||
| Camk2d | 126.3 | 126.55 | Yes | ||
| Ank2 | 126.62 | 126.70 | Yes | Yes | |
| 4930422G04Rik | 127.26 | 127.32 | Yes | Yes | |
| Alpk1 | 127.37 | 127.48 | Yes | Yes | Yes |
Abbreviations: QTL, quantitative trait locus; SNP, single nucleotide polymorphism.
The QTL interval was reduced by fine mapping and by excluding identical-by-descent haplotype blocks. Coding-non-synonymous SNP in Vcam1 (rs13477355) was verified by sequencing. Gene symbols and locations are given according to NCBI mouse build 37.1.