Table 4.
Stability of lumefantrine plasma samples and stocks.
| Storage conditions | LF level (ng/mL) | % Remaining | % RSD |
|---|---|---|---|
| 3 freeze/thaw cycles | Low (120) | 99.5 | 3.0 |
| High (9000) | 102.9 | 1.1 | |
| −70 °C for 9 months | Low (120) | 99.4 | 3.8 |
| High (9000) | 102.5 | 5.4 | |
| benchtop 6 days | Low (120) | 100.6 | 2.6 |
| High (9000) | 98.9 | 1.8 | |
| dry residue 18 hr | Low (120) | 104.8 | 7.2 |
| High (9000) | 93.9 | 6.0 | |
| dry residue 48 hr | Low (120) | 57.4 | 8.1 |
| High (9000) | 65.7 | 17 | |
| in LC solvent 48 hr | Low (120) | 92.7 | 9.3 |
| High (9000) | 95.3 | 4.3 | |
| −70 °C for 9 months | LF Stock solution | 102 | 1.5 |
| 22 °C, 3 days | LF Stock solution | 100 | 2.8 |