Table 2.
Clinical Features of African-American Participants in CHS
| Parameter | A.Fib. | CHF | CHF>70 | Death @ 15 yrs |
|---|---|---|---|---|
| All Consenting CHS Participants | ||||
| V122I | 0/11 | 5/17 | 5/13 | 13/17 |
| V122V | 9/591 | 172/788 | 79/538 | 414/788 |
| RR | 0 | 1.35 | 2.62 | 1.46 |
| 95% CI | 0.64 – 2.86 | 1.28 – 5.37 | 1.11 – 1.91 | |
| P | 0.55 | 0.04 | 0.08 | |
| Age and Gender Comparable CHS Participants | ||||
| V122I | 0/11 | 5/17 | 5/13 | 13/17 |
| V122V | 1/79 | 19/88 | 16/67 | 36/88 |
| RR | 0 | 1.36 | 1.75 | 1.87 |
| 95%CI | 0.59 – 3.15 | 0.79 – 3.86 | 1.30 – 2.69 | |
| P | 0.5 | 0.29 | 0.009 | |
N.A. = not available; RR = relative risk, the risk of the particular clinical feature in the V122I allele carriers relative to the corresponding risk in the V122V controls ; CI = confidence interval.
*
by logrank