Table 3.

Echocardiographic Measurements TTR V122I vs TTR V122V Carriers in CHS and ARIC

Parameter	V122V			V122I
	25%	Median	75%	25%	Median	75%	P
CHS All Consenting African-Americans
LVM	116	144	179	121	151	175	0.80
E/A	0.67	0.79	0.92	0.65	0.77	0.87	0.40
IVSs	1.34	1.49	1.64	1.42	1.67	1.96	0.10
IVSd	0.81	0.92	1.04	0.89	0.96	1.11	0.26
LVWs	1.35	1.49	1.65	1.43	1.79	2.02	0.06
LVWd	0.80	0.89	1.0	0.89	0.96	1.12	0.14
CHS Age and Gender Comparable African-Americans
LVM	105	128	165	121	151	175	0.35
E/A	0.69	0.78	0.90	0.65	0.77	0.87	0.47
IVSs	1.33	1.47	1.62	1.42	1.67	1.96	0.09
IVSd	0.81	0.89	1.05	0.89	0.96	1.11	0.13
LVWs	1.32	1.47	1.67	1.43	1.79	2.02	0.06
LVWd	0.79	0.89	1.01	0.78	0.96	1.12	0.07
ARIC All Consenting African-Americans
LVM	195	242	246	208	246	305	0.43
E/A	0.83	1.00	1.2	0.91	1.04	1.2	0.11
IVSs	1.38	1.54	1.75	1.34	1.50	1.79	0.78
IVSd	1.0	1.13	1.28	1.01	1.14	1.26	0.74
LVWs	1.58	1.74	1.95	1.57	1.67	1.89	0.47
LVWd	1.02	1.13	1.27	1.05	1.13	1.27	0.77

All comparisons were done by Mann-Whitney non-parametric analysis. The comparisons showing statistical trends are signified by the bold font in the P-value column.