FIG. 2.

Profiles of selected blood parameters over time after intrahepatic administration of saline (solid squares) or 7.59 × 10⁹ TCID₅₀ of VSV-hIFNβ (shaded triangles) into Harlan Sprague Dawley rats. Each cohort of rats was alternately bled via the retro-orbital plexus (at 1 hr and day 1) or via nonterminal cardiac puncture (days 2–28) to monitor acute or subacute changes in hematology, coagulation, and clinical chemistry parameters. ALP, alkaline phosphatase; ALT, alanine aminotransferase; APTT, activated partial thromboplastin time; Plt, platelet count; WBC, white blood cell count.