Profiles of body weight and selected blood parameters of rhesus macaques injected intrahepatically with 109 TCID50 (animals 5M02 and 5M03) or 1010 TCID50 (animals 5M04 and 5M05) of VSV-hIFNβ. (A) Representative CT images showing virus administration into the hepatic lobes of 5M02 and 5M04. (B) Measurements of body weight over time, taken on day 4 prestudy or after viral administration. (C) A selection of measured blood analytes is shown. ALT, alanine aminotransferase; ALP, alkaline phosphatase; ALB, albumin; WBC, white blood cells; PLT, platelets; TBIL, total bilirubin. Dotted lines represent normal reference ranges of rhesus macaques. Shaded squares, 5M02; solid triangles, 5M03; open circles, 5M04; open diamonds, 5M05.