Table 3b.
Specific genes contributing to enrichment of the term “cellular lipid metabolic process”
| Gene | Rank in GWAS | Marker | p-value (original) |
|---|---|---|---|
| CETP | 1 | rs7203984 | 4.55E-20 |
| LPL | 2 | rs328 | 2.29E-11 |
| LIPC | 3 | rs1077834 | 5.18E-10 |
| ABCA1 | 7 | rs4149274 | 7.36E-08 |
| MVK | 17 | rs7954144 | 4.76E-06 |
| FADS1 | 21 | rs174545 | 4.18E-05 |
| LYPLA3 | 26 | rs17688076 | 4.18E-05 |
| PPARA | 99 | rs9615264 | 4.44E-05 |
| SMPD2 | 120 | rs6911838 | 1.14E-03 |
| BMP6 | 136 | rs2876117 | 5.15E-05 |
| CPT1A | 147 | rs597539 | 1.53E-04 |
| LCAT | 151 | rs4986970 | 1.07E-03 |
| ADIPOR2 | 160 | rs11061935 | 1.79E-04 |
Rank in GWAS is according to the LD-adjusted p-value of the most significant marker associated with each gene. The presented p-value is the unadjusted significance of the specified marker in the original data set.