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Effects of DOA disease mutations in liposome-binding and GTP hydrolysis activity. (A) Liposome binding was measured by a liposome co-sedimentation assay, as in Fig. 2A. (B–D) GTP hydrolysis activity was measured at 300 mm NaCl (B), 0 mm NaCl (C) and 300 mm NaCl with cardiolipin-containing liposomes (D).
