Table 2.
Maximum percent drug-appropriate responding (DAR) of each test compound in each of the training groups and effects on rate of responding at that dose.
| Training Drug | Test Compound | Dose (mg/kg) | N Test | %DAR | Rate resp/s |
|---|---|---|---|---|---|
| DMT | Saline | 0 | 6/6 | 0.0±0.0 | 1.102±0.101 |
| DMT | DMT | 5 | 6/6 | 96.6±2.4 | 0.575±0.119 |
| DMT | DOM | 1 | 4/6 | 97.7±1.8 | 0.293±0.175 |
| DMT | LSD | 0.1 | 6/6 | 100.0±0.0 | 1.011±0.066 |
| DMT | MDMA | 3 | 5/6 | 80.0±19.3 | 0.551±0.155 |
| DMT | Meth | 0.5 | 6/6 | 32.2±20.4 | 1.062±0.137 |
| DOM | Saline | 0 | 6/6 | 16.9±16.6 | 1.384±0.146 |
| DOM | DOM | 0.5 | 6/6 | 99.9±0.1 | 0.768±0.171 |
| DOM | DMT | 5 | 5/6 | 82.8±14.8 | 0.078±0.034 |
| DOM | LSD | 0.1 | 6/6 | 82.8±16.6 | 0.742±0.200 |
| DOM | MDMA | 3 | 5/6 | 89.1±9.3 | 0.835±0.225 |
| DOM | Meth | 2 | 5/6 | 20±20 | 1.089±0.271 |
| LSD | Saline | 0 | 6/6 | 0.2±0.2 | 0.900±0.097 |
| LSD | LSD | 0.1 | 6/6 | 83.3±16.7 | 1.199±0.092 |
| LSD | DMT | 2.5 | 6/6 | 56.3±19.8 | 0.686±0.146 |
| LSD | DOM | 0.25 | 6/6 | 83.3±16.7 | 1.017±0.098 |
| LSD | MDMA | 3 | 6/6 | 56.1±18.5 | 0.591±0.200 |
| LSD | Meth | 2.5 | 3/6 | 24.1±24.1 | 0.538±0.316 |
| MDMA | Saline | 0 | 6/6 | 0.1±0.1 | 1.253±0.172 |
| MDMA | MDMA | 1.5 | 6/6 | 99.8±0.2 | 0.994±.221 |
| MDMA | DMT | 5 | 4/6 | 49.5±26.9 | 0.184±0.137 |
| MDMA | DOM | 0.25 | 6/6 | 51.1±21.4 | 1.113±0.151 |
| MDMA | LSD | 0.1 | 5/6 | 84.6±14.2 | 0.286±0.162 |
| MDMA | Meth | 2.5 | 4/6 | 92.2±4.7 | 0.266±0.11 |
| Meth | Saline | 0 | 6/6 | 0.0±0.0 | 1.297±0.137 |
| Meth | Meth | 1 | 6/6 | 98.2±1.0 | 0.855±0.165 |
| Meth | DOM | 0.5 | 6/6 | 15.4±15.1 | 1.075±0.212 |
| Meth | DMT | 1 | 6/6 | 37.0±19.9 | 1.195±0.154 |
| Meth | LSD | 0.05 | 5/6 | 38.1±23.1 | 0.745±0.207 |
| Meth | MDMA | 3 | 4/6 | 82.3±6.4 | 0.061±0.046 |
N Test = number of rats which completed the first fixed ratio/total number tested. resp/s = responses per second.