Anti-CD79 reduced inflammation in kidney and submandibular salivary glands. MRL/lpr-Thy1.1 female were given six weekly injections of either PBS or anti-CD79α and anti-CD79β Abs (AB) (Table II, Expt. IV; n = 5 mice/group). Shown are representative H&E-stained sections (×100 magnification) of kidneys (A and B) and submandibular salivary glands (C and D). Circled in red are inflammatory infiltrates. b, blood vessel; d, glandular duct. E, Number of focal inflammatory infiltrates in kidneys and submandibular salivary glands. *, p < 0.05 by two-tailed Student’s t test. F, Scores of glomerulonephritis and interstitial nephritis. Significance was determined by two-tailed Fisher’s exact test.