Table 2.
Frequency of PI3KCA mutations found in 264 gastric cancers, by mutation type.
| Mutation | Overall frequency (MSI only) |
Percent/total cases | Percent/mutated cases | |
|---|---|---|---|---|
| Exon 9 | E542K | 2 | 0.76% | 4.76% |
| E545K | 2 | 0.76% | 4.76% | |
| Q546K | 4 | 1.52% | 9.52% | |
| Total Mutations (ex. 9) | 8 | 3.03% | ||
| Exon 20 | M1043V | 1 | 0.38% | 2.38% |
| H1047R | 26 (8) | 9.85% | 61.90% | |
| H1048T | 1 | 0.38% | 2.38% | |
| G1050D | 2 | 0.76% | 4.76% | |
| T1052I | 1 | 0.38% | 2.38% | |
| T1053I | 1 | 0.38% | 2.38% | |
| D1056N | 2 | 0.76% | 4.76% | |
| L1067F | 1 | 0.38% | 2.38% | |
| Total Mutations (ex.20) | 35 | 13.26% | ||
| Total Mutations | 42 | 15.91% | ||