Skip to main content
. 2010 Apr 8;5:13. doi: 10.1186/1750-1326-5-13

Figure 3.

Figure 3

PLA2 inhibitors protected against Aβ1-42 induced synapse degeneration. (A) The synaptophysin content of cortical neurones pre-treated with a vehicle control (■), 1 μM AACOCF3 (○) or 1 μM MAFP (●) and incubated with varying concentrations of Aβ1-42 for 24 hours. Values shown are the mean average amount of synaptophysin ± SD, n = 12. (B) The synaptophysin content of hippocampal neurones pre-treated with a vehicle control (■) or 1 μM AACOCF3 (○) and incubated with varying concentrations of Aβ1-42 for 24 hours. Values shown are the mean average amount of synaptophysin ± SD, n = 6.