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. 2010 Apr 8;5:13. doi: 10.1186/1750-1326-5-13

Figure 4.

Figure 4

PLA2 inhibitors protected against 7PA2-CM induced synapse degeneration. (A) The synaptophysin content of cortical neurones incubated for 24 hours with 7PA2-CM (□) or CHO-CM (■). Values shown are the mean average amount of synaptophysin ± SD, n = 12. (B) The synaptophysin content of cortical neurones incubated for pre-treated with a vehicle control (□), 1 μM AACOCF3 (■) or 1 μM MAFP (striped bars) and incubated with doubling dilutions of 7PA2-CM for 24 hours. Values shown are the mean average amount of synaptophysin ± SD, n = 12.