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Prostaglandin E2 caused synapse degeneration. The synaptophysin content of cortical neurones treated with varying concentrations of prostaglandins E2 (●) D2 (○), F2α(□), I2 (■) or 15d-J2 (▲) for 24 hours. Values shown are the mean average amount of synaptophysin ± SD, n = 9.
