Table 4.
Association of 2-year change in physical functioning score and 2-year change in measures of cognitive function
| Symbol Digit Modality Test |
Digit Span Backward Test |
East Boston Memory Test |
||||
|---|---|---|---|---|---|---|
| β (SE) | p value | β (SE) | p value | β (SE) | p value | |
| Basic models1 | ||||||
| Standardized cognitive measure | 2.170 (0.829) | 0.004 | −0.185 (0.814) | 0.410 | 2.064 (0.841) | 0.007 |
| Time | 0.011 (0.192) | 0.476 | 0.162 (0.192) | 0.199 | 1.50 (0.191) | 0.216 |
| Time × standardized cognitive measure | −0.052 (0.125) | 0.388 | 0.126 (0.129) | 0.164 | −0.231 (0.139) | 0.048 |
| Expanded models2 | ||||||
| Standardized cognitive measure | 1.520 (0.878) | 0.041 | 0.127 (0.139) | 0.280 | 1.917 (0.898) | 0.016 |
| Time | 0.119 (0.194) | 0.268 | 0.209 (0.191) | 0.138 | 1.188 (0.191) | 0.162 |
| Time × standardized cognitive measure | −0.087 (0.135) | 0.256 | 0.127 (0.139) | 0.180 | −0.256 (0.150) | 0.044 |
1
Basic models relate physical function change with changes in four different cognitive function assessments, adjusted for age, race, and study site.
2
Expanded models additionally adjusted for education, difficulty paying for basics, metabolic syndrome status, depressive symptoms, and menopause status.