Skip to main content
. 2010 May 6;6(5):e1000896. doi: 10.1371/journal.ppat.1000896

Figure 7. Genetic diversity of SARS-WT and S-ExoN1 from P1', P5', and P10'.

Figure 7

(A) The percentage of reads within each sample that have 0-1 (left) or 2–3 (right) mismatches compared to the corresponding reference sequence are shown. (B) RMSD plots. For each SARS-WT sample (a–d) or S-ExoN1 sample (e–h) the root mean squared deviation (RMSD) from the corresponding reference sequence is plotted for each nucleotide position in the genome. Plots are for P1' (a, e), P5' (b, f), P10' (c, g), or combined P1', P5', and P10' (d, h). The maximal RMSD value of 0.632 indicates completely different single-allelic distributions between experimental and reference sequences whereas values ≤0.0125 (dashed line) were considered background. (C) Summary RMSD values between SARS-WT P1', P5', or P10' or S-ExoN1 P1', P5', or P10' and reference sequences were calculated by computing the arithmetic mean of each RMSD value for every position in the genome. The 95% confidence intervals are indicated by error bars.